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Journal Name:
Analytical Letters
Volume:
21
Issue:
10
Pages From:
1845
To:
1853
Date:
Saturday, October 1, 1988
Keywords:
Ranitidine, D. C. Polarography, Pharmaceutical Formulations, Drug Analysis
Abstract:
A simple, accurate and rapid method for the quantitative determination of five ranitidine drugs in pharmaceutical formulations (Tablets and Ampoules) is proposed. The supporting electrolyte was acetic acid-sodium acetate buffer solution (pH 5.2). An excellent linear relationship was obtained between the concentration and current with correlation coefficient 0.9996. Good agreement was obtained between the results with the d.c. polarograhic method and those by the manufacturer's method of assay.